Nootropic drugs reduce immobility in behavioural despair test in mice
Schmidt, J.
Biomedica Biochimica Acta 43(11): 1295-1299
1984
ISSN/ISBN: 0232-766X PMID: 6442578 Document Number: 224374
The effect of different nootropic drugs (piracetam, pyritinol, meclofenoxate, methylglucamine orotate, dihydroergotoxine, nicergoline, vinpocetine) on the duration of immobility in the behavioral despair test in mice was studied. All nootropics tested exhibited a dose-related reduction in immobility. In connection with the discussed role of monoaminergic processes in the state of immobility data support the possible participation of central monoaminergic systems in the mechanisms of action of nootropic drugs.