Significance of antinuclear anti-histone antibodies
Ferec, C.; Youinou, P.; Le Goff, P.; Miossec, P.; Morin, J.F.; Pennec, Y.; Morin, P.P.; Le Menn, G.
Annales de Medecine Interne 135(6): 427-430
1984
ISSN/ISBN: 0003-410X PMID: 6334466 Document Number: 224059
The results of routine antihistone antibody (AHA) assay in a preliminary series of 189 sera are presented. There were 23 positive tests (systemic lupus erythematosus, 8 cases; drug induced SLE, 4 cases; rheumatoid arthritis 7 cases; and multiple sclerosis, 1 case; chronic active hepatitis, 1 case; systemic sclerosis, 1 case and primary biliary cirrhosis 1 case). The results of routine assay in 5 other patients groups are reported: 30 spontaneous SLE (9 positive AHA), 63 rheumatoid arthritis (2 positive AHA), 19 Sjögren syndrome (no AHA), 11 primary biliary cirrhosis (1 positive AHA) and 7 mixed connective tissue disease (no AHA).