Action of CDP-choline by intraduodenal route on rat cardiorespiratory system
Brasó, M.A.; Sacristán, A.; Ortiz, J.A.
Arzneimittel-Forschung 33(7a): 1043-1045
1983
ISSN/ISBN: 0004-4172 PMID: 6684462 Document Number: 216781
The influence of an acute treatment with cytidine diphosphate choline (CDP-choline, citicoline, Somazina) by intraduodenal route on cardiovascular and respiratory parameters in anesthetized rats is studied. No differences as compared with controls were observed in heart and respiratory rates. The values in arterial pressure and respiratory flow for CDP-choline groups were observed to be near the basal values. The inspiratory flow shows a statistically significant difference (approaching basal values) as compared with the decrease in controls.