Thrombocythemia with Philadelphia chromosome. Secondary appearance of chronic myeloid leukemia
Vannier, J.P.; Schaison, G.; Valensi, F.; Berger, R.; Tanzer, J.
Presse Medicale 12(42): 2683-2684
1983
ISSN/ISBN: 0755-4982 PMID: 6228817 Document Number: 215228
The finding of a Philadelphia chromosome in a case of apparently primary thrombocythaemia should change the diagnosis for that of chronic myeloid leukaemia. This theoretical view is supported by the case reported here, where a Philadelphia-chromosome was detected in the bone marrow cells of a patient with severe thrombocythaemia; a typical myeloid leukaemia developed 21 months after the onset of the disease; survival was of short duration.
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