Biological properties of immunochemically pure tetanus antitoxin
Kornilova, A.V.; Khavkin, I.A.; Batalova, T.A.; Aleksevich, I.I.; Baschenko, I.A.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2: 66-70
1983
ISSN/ISBN: 0372-9311 PMID: 6340393 Document Number: 215134
Immunochemically pure tetanus antitoxin obtained from enzyme-treated horse serum is less reactogenic and anaphylactogenic and possesses higher therapeutic properties than antitoxin purified by nonspecific physico-chemical methods and containing ballast antigens. Due to its increased persistence in the recipient's body, the immunochemically pure antitoxin induces passive immunity in considerably lower doses than the preparations purified by the method "Diaferm-3".