Microtubule-associated protein MAP2 preferentially binds to a dA/dT sequence present in mouse satellite DNA

Avila, J.; Montejo de Garcini, E.; Wandosell, F.; Villasante, A.; Sogo, J.M.; Villanueva, N.

EMBO Journal 2(8): 1229-1234

1983


ISSN/ISBN: 0261-4189
PMID: 10872313
Document Number: 212885
Microtubule-associated protein MAP2 binds to the Sau96.1 restriction monomer fragment of mouse satellite DNA. This fragment is also present in a lower proportion in bulk DNA. The digestion of MAP2-Sau96.1 fragment complex by DNase results in the protection of certain nucleotide sequences. The sequence poly(dA)4/poly(dT)4 is mainly protected against DNase digestion.

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