Expression changes of tau protein and microtubule-associated proteins in testis intersitium of rats
Liu, Z.; Wang, G.; Zhang, W.; Liu, S.; Wang, X.; Wang, F.; Kang, X.
Zhonghua Nan Ke Xue 10(1): 35-38
2004
ISSN/ISBN: 1009-3591 PMID: 14979206 Document Number: 583216
To examine the expression of the tau protein and microtubule-associated proteins in the testis interstitium of aged and young rats. Sprague-Dawley male rats were divided into a young group(6 months, n = 10) and an aged group(28 months, n = 10). The two steps immunohistochemistry method with the antibody against tau protein and MAP alpha was performed on the testis tissues of the rats. The results showed that the immunoreactive cells of tau protein of the testis interstilial of the aged rats obviously increased(P < 0.001) than those of the young, while the immunoreactive cells of the microtubule-associated proteins decreased(P < 0.01) in the aged. The changes in the expression of the tau protein and microtubule-associated proteins may be related to the aging process of the testis.