Effect of tumor antigens on leukocyte adherence in the blood in stomach cancer
Zharkov, V.V.; Novikov, D.K.
Voprosy Onkologii 29(2): 14-18
1983
ISSN/ISBN: 0507-3758 PMID: 6836968 Document Number: 212406
The reaction of changes in leukocyte adherence was compared in 79 cases of stomach cancer, 44 cases of other gastric diseases and healthy subjects. Tumor antigens were shown to inhibit the adherence of lymphocytes and granulocytes in 61 out of 79 cancer patients (77,2%); adherence inhibition was more frequently observed in patients with stage I-III tumors than in cases of stage IV tumors. The removal of the antigens of normal mucosa from tumor tissue extracts did not affect the frequency of positive reactions in cancer patients significantly. However, the frequency dropped from 22-34 to 2.3-13.6% in the group of non-tumor patients.