Comparative cost-effectiveness of three intrauterine devices: a multi-center randomized trial
Wen, J.; Li, Y.; Li, Y.; Wang, L.; Zhou, J.; Ba, L.; Shen, S.; Wu, Y.
Journal of Evidence-Based Medicine 3(2): 76-82
2010
ISSN/ISBN: 1756-5391 PMID: 21349048 DOI: 10.1111/j.1756-5391.2010.01075.xDocument Number: 211125
To determine the relative cost-effectiveness of three intrauterine devices (IUDs), MLCu375, TCu380A, and YuangongCu365. Cost-effectiveness of three IUDs, namely MLCu375, TCu380A, and YuangongCu365, was analyzed from the provider's perspective by means of a randomized trial with one-year follow-up carried out in six centers in China. YuangongCu 365 had the lowest termination and pregnancy rates (4.17% and 0.54%, respectively), followed by TCu380A (8.59% and 1.11%, respectively) and MLCu375 (14.17% and 2.04%, respectively). YuangongCu365 was more effective yet more costly than the MLCu375. There was a favorably dominating trend of cost-effectiveness for TCu380A comparing with MLCu375 when taking continuation rate as the effectiveness indicator, but there was no difference in cost-effectiveness between the two IUDs when using the pregnancy avoidance rate as the effectiveness measure. TCu380A is slightly more cost-effective than the MLCu375. YuangongCu365 is the most effective of the three devices and be used provided it is economically affordable. The comparative long-term safety and cost-effectiveness of these devices need to be further investigated.