The cost effectiveness of auranofin: results of a randomized clinical trial
Thompson, M.S.; Read, J.L.; Hutchings, H.C.; Paterson, M.; Harris, E.D.
Journal of Rheumatology 15(1): 35-42
1988
ISSN/ISBN: 0315-162X PMID: 3127585 Document Number: 309110
In a 6-month randomized trial at 14 sites, the cost effectiveness of auranofin (AF) treatment for patients with rheumatoid arthritis was gauged in comparison with placebo. Measures of global health and of impacts on daily life suggest that the benefits of disease modification outweigh adverse effects after 4 and 6 months of treatment (p less than 0.01), with negligible differences between placebo and treated patients after 1 and 2 months. Additional medical costs directly associated with AF treatment amounted to $778/patient annually. Observed differences in less direct medical costs, help received, and earnings were not statistically significant.
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