Clinical results of cefpiramide therapy in infections of children
Nagamatsu, I.; Okuno, A.
Japanese Journal of Antibiotics 36(8): 2147-2152
1983
ISSN/ISBN: 0368-2781 PMID: 6655834 Document Number: 208546
Twenty-one pediatric patients with moderate or severe infections were treated with cefpiramide (CPM). The drug was given intravenously in a dose of 10 approximately 52.3 mg per kg at 8 approximately 12 hourly interval. All 7 patients with urinary tract infection, 4 with bacterial enteritis and 4 out of 7 patients with lower respiratory tract infections responded satisfactory, but 2 patients with either Serratia marcescens septicemia or H. influenzae meningitis not responded to treatment. Over all response rate was 71.4 percent. There was no change in test of liver and renal function. CPM appears to be effective and well-tolerated antibiotics for the treatment of pediatric patients with various infections.