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Translational inhibition of heat-shock induced gene expression in picornavirus-infected Drosophila melanogaster cells

Reavy, B.; Pullin, J.S.; Moore, N.F.

Microbios 38(152): 91-98

1983

ISSN/ISBN: 0026-2633
PMID: 6316114
Document Number: 207801
Picornavirus infection of Drosophila melanogaster cells inhibited the appearance of heat-shock induced proteins. Examination of intracellular mRNAs revealed that those coding for heat shock proteins were present in a translationally competent form in infected cells. Inhibition of induced gene expression in infected Drosophila cells therefore involves, but is not necessarily solely mediated by, effects at the level of translation.

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