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An EEG investigation on the effects of phencyclidine on pentylentetrazol convulsions in rats and rabbits

Sagratella, S.; Passarelli, F.; Scotti de Carolis, A.

Archives Internationales de Pharmacodynamie et de Therapie 266(2): 294-307

1983

ISSN/ISBN: 0003-9780
PMID: 6667070
Document Number: 205756
The present work deals with an EEG and behavioral study of the effect of phencyclidine against the convulsions due to pentylentetrazol in rats and rabbits. The effects of phencyclidine were compared to those of phenobarbital and trimethadione. A dissociation between the behavioral and electrocortical manifestations of chemically-induced convulsions in the presence of several anticonvulsant drugs has been found.

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