Antihistaminic effect of a hydrogel with the components diphenhydramine, N,N-diethyl-m-toluamide and phthalic acid dimethyl ester

Oelschläger, H.; Rothley, D.

Arzneimittel-Forschung 33(1): 169-172

1983


ISSN/ISBN: 0004-4172
PMID: 6131676
Document Number: 205167
The combination of the antihistamine diphenhydramine as well as the repellents N,N-diethyl-m-toluamide and dimethylphthalate as the active constituents of an insect repellent (Pellit) guarantees a remarkable antihistaminic effect. Surprisingly the repellent N,N-diethyl-m-toluamide proved itself to be an antihistamine. The UV-erythema model was used on the dorsal skin of male volunteers.

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