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Changes in plasma renin activity (PRA) , angiotensin I and placental leucine aminopeptidase (P-LAP) activity during normal pregnancy

Mizutani, S.; Sakura, H.; Akiyama, H.; Kobayashi, H.

Nihon Sanka Fujinka Gakkai Zasshi 35(4): 545-549

1983

ISSN/ISBN: 0300-9165
PMID: 6343531
Document Number: 204822
Plasma renin activity (PRA) and relative changes in angiotensin I compared with non-pregnant women were determined by radioimmunoassay (RIA) at different stages of normal gestation. Their levels showed increases in the early and late stages, and decreases at the period of 25 to 28 weeks of pregnancy in the middle stage, although their levels were higher than those in non-pregnant women throughout pregnancy. The increase in angiotensin I was less striking than that of PRA. Placental leucine aminopeptidase (P-LAP) activity increased progressively with advancing gestation, reaching the highest value at the 38th week of pregnancy. Simultaneous estimations of changes in angiotensin I and placental leucine aminopeptidase (P-LAP) were performed longitudinally in 12 normal pregnant women. The significance of the increase in P-LAP activity and the relationships among PRA, angiotensin I and P-LAP during normal pregnancy are discussed.

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Mizutani, S.; Sakura, H.; Inamoto, Y.; Noto, H.; Kawashima, Y. 1982: Inactivation of oxytocin and angiotensin II by placental leucine aminopeptidase (P-LAP) Nihon Sanka Fujinka Gakkai Zasshi 34(4): 545-547
Christensen, A. 1974: Hormone and enzyme assays in pregnancy. I. Studies on the placental and the tissue cystine-aminopeptidase activity in peripheral plasma from non-pregnant and pregnant women, and in plasma from the umbilical cord Acta Endocrinologica 76(1): 189-200
Onicescu, D.; Marin, A.; Mischiu, L. 1976: Histoenzymatic activity of leucine aminopeptidase in normal bone marrow cells Morphologie et Embryologie 22(3): 167-170
Kokot, F.; Cekański, A. 1970: Behavior of the plasma renin activity in normal pregnancy, in pregnancy toxemias and in the umbilical cord blood of the newborn Zentralblatt für Gynakologie 92(9): 280-287
Cekański, A.; Kokot, F.; Poreba, R.; Ayuk Mbu, J. 1981: Renin activity and plasma aldosterone levels in ulnar and uterine veins and in cord blood in normal pregnancy and pregnancy toxemias Ginekologia Polska 52(1): 15-20
Drozdz, H.; Dobrzyńska-Ogniewska, W. 1978: Effects of glucocorticoids on enzyme activity in viral hepatitis. I. Behavior of serum leucine aminopeptidase and glycine aminopeptidase Folia Medica Cracoviensia 20(2): 263-274
Larochelle, P.; Genest, J.; Kuchel, O.; Boucher, R.; Gutkowska, Y.; McKinstry, D. 1979: Effect of captopril (SQ 14225) on blood pressure, plasma renin activity and angiotensin I converting enzyme activity Canadian Medical Association Journal 121(3): 309-316
Rydén, G. 1972: Cystine aminopeptidase activity in pregnancy. II. Its clinical application as an index of placental function Acta Obstetricia et Gynecologica Scandinavica 51(4): 329-334
Vallotton, M.B. 1971: Parallel radioimmunoassays of angiotensin i and of angiotensin Ii for measurement of renin activity and of circulating active hormone in human plasma Hormone and Metabolic Research 3(Suppl 3): 94-100
Mojzís, A.; Vokurková, I. 1972: Activity of leucine aminopeptidase in urine Vnitrni Lekarstvi 18(10): 969-973
Grigor'eva, Z.E. 1976: Activity of blood plasma renin and angiotensin in patients with hypertensive disease Vrachebnoe Delo 10: 78-80
Michel, B.; Grima, M.; Coquard, C.; Welsch, C.; Barthelmebs, M.; Imbs, J.L. 1993: Plasma renin activity and angiotensin converting enzyme of renal brush borders Archives des Maladies du Coeur et des Vaisseaux 86(8): 1245-1248
Muangmanee, L.; Suwanik, R.; Pattanachak, C.; Sravich, S.; Jaroonvesama, N. 1976: Plasma renin activity in normal Thais Journal of the Medical Association of Thailand 59(5): 208-213
Collart, F.; Staroukine, M.; Verniory, A. 1985: Relationships between blood pressure, heart rate and plasma epinephrine, norepinephrine, angiotensin II concentrations, plasma renin activity during chronic guanfacine therapy in patients with essential arterial hypertension Acta Cardiologica 40(3): 269-276
Popova, S.; Beleva-Staĭkova, R.; Bozukova, T. 1978: Changes in serum leucine aminopeptidase activity during halothane anesthesia with and without thiopental administration Khirurgiia 31(6): 516-520
Kawai, M.; Hara, Y.; Kubota, T.; Shiba, K.; Hosaki, S. 1998: A family with high serum leucine aminopeptidase activity derived from a novel variant CD13 Clinical Chemistry 44(2): 215-220
Aoyama, K.; Ogata, M.; Sata, T.; Shigematsu, A. 1992: Plasma levels of alpha-human atrial natriuretic peptide, renin activity and angiotensin Ii in partial hepatectomy MASUI. Japanese Journal of Anesthesiology 41(1): 37-42
Brandes, J.M.; Abramovici, H.; Katz, M.; Diengott, D.; Spindel, A.; Kahana, L. 1978: The effect of postural changes on plasma renin activity during normal and pathologic pregnancies Obstetrics and Gynecology 52(5): 530-532
Musumeci, V.; Baroni, S.; Cardillo, C.; Zappacosta, B.; Zuppi, C.; Tutinelli, F.; Folli, G. 1987: Cardiovascular reactivity, plasma markers of endothelial and platelet activity and plasma renin activity after mental stress in normals and hypertensives Journal of Hypertension. Suppl: Official Journal of the International Society of Hypertension 5(5): S1-S4
Forette, F.; Ménard, J.; Forette, B.; Henry, J.F.; Berthaux, P. 1978: Plasma renin activity in normal and hypertensive aged subjects. Preliminary results Annales de Medecine Interne 129(6-7): 399-403