Antibodies to hepatitis a and B viral antigens in commercial gamma-globulin preparations
Viazov, S.O.; Doroshenko, N.V.; Khatkevich, S.P.; Reznikov, I.P.; Minakova, L.V.
Voprosy Virusologii 28(5): 542-545
1983
ISSN/ISBN: 0507-4088 PMID: 6197815 Document Number: 203965
Radioimmunoassay was used to study the presence of antibodies to hepatitis A and B virus antigens in commercial gamma-globulin preparations produced in 20 towns of the USSR. Antibodies to hepatitis A virus were found in all gamma-globulin lots tested, their titres varying from 1:10 to 1:1000. Anti-HBs in titres from 1:1 to 1:32 were found only in 66% of the lots tested, being present in all the lots produced in Moscow and Gorkiy and only in half of the lots produced in Tashkent. Antibodies to HBcAg and HBeAg of hepatitis B virus were found in all the lots gamma-globulin tested, their titres falling within the range of 1:100 1:4000 (anti-HBc) and 1:32-1:64 (anti-HBe).