Top Abstract Purchase Related
Home
>
Node
>
Subnode

Splenic accumulation of stromal progenitor cells in response to bacterial lipopolysaccharides

Brockbank, K.G.; Ploemacher, R.E.; van Peer, C.M.

Experimental Hematology 11(5): 358-363

1983

ISSN/ISBN: 0301-472X
PMID: 6852146
Document Number: 202476
An analysis was made of fibroblastoid colony-forming units (CFUF) in spleens of mice treated with bacterial lipopolysaccharide (LPS). Increased CFUF numbers were observed on days 2, 3 and 4 after treatment with 10, 30 and 100 micrograms of LPS. The splenic CFUF accumulation occurred at the same time as spleen hemopoiesis increased, however, the CFUF returned to normal and subnormal numbers on day 5, while the spleen cellularity was still elevated on day 21 after LPS treatment. The mechanism of splenic CFUF accumulation appeared to involve CFUF migration via the blood from other sites of hemopoiesis rather than increased CFUF plating efficiency in vitro or enhanced CFUF proliferation. The results suggest a relationship between the LPS-induced fibroblastoid progenitor cell increase and a requirement for splenic microenvironments to support LPS-induced hemopoiesis.

Document emailed within 1 workday
Secure & encrypted payments

Shek, P.N. 1977: Enhancement of the DNA synthetic response of antigen-primed lymph node cells by splenic promoter cells: characterization of the splenic promoter cells Journal of Immunology 119(1): 83-90
Thorvaldson, J.; Stokland, O.; Ilebekk, A. 1990: Effects of increased splenic arterial flow and venous pressure on splenic red cell accumulation American Journal of Physiology 258(3 Pt 2): H669-H678
Heyworth, C.M.; Dexter, T.M. 1988: The development of hemopoietic cells in response to stromal cells or growth factors is modified by agents that influence ADP-ribosylation Leukemia 2(1): 6-11
Numata, M.; Koizumi, S.; Horita, S.; Ueno, Y.; Yamagami, M.; Taniguchi, N. 1985: Different Ia antigen characterization between granulocyte progenitor cells (CFC-G) and monocyte-macrophage progenitor cells (CFC-M) Experimental Hematology 13(8): 827-832
Zielińska-Kuźniarz, K.; Mieszała, M.łg.; Lipiński, T.; Gamian, A. 2003: Glycine as an inherent component of bacterial lipopolysaccharides Postepy Higieny i Medycyny Doswiadczalnej 57(5): 473-483
Perelygin, N.L.; Perelygina, O.V.; Babichev, V.A.; Uteshev, B.S. 1975: RNA biosynthesis in the microsomes of splenic cells during the inductive phase of the immunological response Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 5: 29-33
Le Gros, G.; Ben-Sasson, S.Z.; Conrad, D.H.; Clark-Lewis, I.; Finkelman, F.D.; Plaut, M.; Paul, W.E. 1990: IL-3 promotes production of IL-4 by splenic non-B, non-T cells in response to Fc receptor cross-linkage Journal of Immunology 145(8): 2500-2506
Langendorff, H.; Langendorff, M.; Weckesser, J.; Steinbach, K.H. 1971: Bacterial lipopolysaccharides and their components as radiation-resistance increasing substances Acta Radiologica. Supplementum 310: 173-180
Larsen, J.H. 1976: The pathogenic significance of bacterial lipopolysaccharides: LPS syndrome. a review and hypothesis Ugeskrift for Laeger 138(9): 538-542
Morrison, D.C.; Kline, L.F. 1977: Activation of the classical and properdin pathways of complement by bacterial lipopolysaccharides (LPS) Journal of Immunology 118(1): 362-368
Grimaz, S.; Damiani, D.; Michieli, M.; Baccarani, M. 2000: Mobilization of peripheral blood progenitor cells with G-CSF alone in lymphoma patients: steady-state circulating progenitor cell count predicts the autograft yield Haematologica 85(1): 102-103
Mergenthaler, H.G.; Staber, F.G.; Hültner, L.; Dörmer, P. 1982: The response of murine splenic granulocyte-macrophage colony-forming cells to lipid a in vivo Experimental Hematology 10(8): 637-649
Averbakh, M.M.; Salov, V.F.; Agal'tsova, S.I.; Prokhorov, V.I.; Apt, A.S. 1995: The specific proliferative response of the splenic T-cells in mice with opposite sensitivity to staphylococcal infection Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 6: 66-67
McArthur, G.A.; Longmore, G.D.; Klingler, K.; Johnson, G.R. 1995: Lineage-restricted recruitment of immature hematopoietic progenitor cells in response to Epo after normal hematopoietic cell transfection with EpoR Experimental Hematology 23(7): 645-654
Toro, F.; Benshimol, A.L.; González Elorriaga, M.; Soyano, A. 1992: Spleen and thymus histology and proliferative response of splenic cells in rats fed raw and cooked Phaseolus vulgaris beans Archivos Latinoamericanos de Nutricion 42(4): 395-402
Jirillo, E.; Miragliotta, G.; Fumarola, D. 1982: Effects of bacterial lipopolysaccharides (LPS) on leukocytes and platelets. Recent views on the pathophysiological role of LPS in the host Bollettino dell'Istituto Sieroterapico Milanese 61(4): 285-293
Ahmann, G.B.; Nadler, P.I.; Birnkrant, A.; Hodes, R.J. 1981: T cell recognition in the mixed lymphocyte response. II. Ia-positive splenic adherent cells are required for non-I region-induced stimulation Journal of Immunology 127(6): 2308-2313
Zhang, K.-j.; Zhu, Y.; Sun, H.-y.; Huang, L.-f.; Fu, J.-r.; Liu, W.-l. 2006: Mechanism of radiation induced premature senescence of bone marrow stromal cells: experiment with murine bone marrow stromal cells Zhonghua Yi Xue Za Zhi 86(48): 3431-3434
Lisovenko, V.G.; Skripnik, S.I.; Zdorovenko, G.M. 1984: Change in the cellular immune response under the influence of lipopolysaccharides Mikrobiolohichnyi Zhurnal 46(2): 28-30
Corcoran, K.E.; Patel, N.; Rameshwar, P. 2007: Stromal derived growth factor-1alpha: another mediator in neural-emerging immune system through Tac1 expression in bone marrow stromal cells Journal of Immunology 178(4): 2075-2082