Morphologic features of the phagocytosis of filamentous forms of bacteria by neutrophilic granulocytes
Pigarevskiĭ, V.E.; Danilova, M.A.; Mazing, I.A.; Kokriakov, V.N.
Arkhiv Patologii 44(3): 59-65
1982
ISSN/ISBN: 0004-1955 PMID: 6805447 Document Number: 195725
A model system has been developed (B. megaterium + granulocyte) imitating the mechanisms of phagocytosis of filamentous forms of bacteria by neutrophilic granulocytes. In the capture of multicellular microbial filaments by one or several granulocytes predominate the mechanisms of cell membrane invagination and formation of exocytic secretory system providing the inhibition of the activity of the phagocytized agent and release of microbicidal factors and enzymes into the extracellular environment. The importance and frequency of occurrence of the observed phenomenon in different pathological forms have not been elucidated.