A study of the correlation between the stromal reaction to the primary lesion and immunological parameters in patients with cervical cancer
Abe, Z.
Nihon Sanka Fujinka Gakkai Zasshi 34(4): 521-528
1982
ISSN/ISBN: 0300-9165 PMID: 7069256 Document Number: 194049
A correlation between the stromal reaction to the primary lesion and the clinical immunoparameters, and prognosis were studied in patients with cervical cancer (stage Ib, II). All patients were treated with curative operation. There was a significant correlation between the degree of stromal reaction and the depth of primary lesion and regional lymph node metastasis (P < 0.05). The degree of stromal reaction was correlated with the positive rate of DNCB skin reaction. The degree of stromal reaction was not correlated with the count of peripheral lymphocytes, monocytes or with the ability of lymphocyte for blastoid transformation. The recurrence rate in marked stromal reaction group was 13.6%; 22.2% in moderate group 28.6% in slight group. There was no significant correlation in the group. Five year survival rate in marked stromal reaction group was 86.4%; 81.5% in moderate group and 71.4% in slight group. There was also no significant correlation in the group.