Pathological hyperprolactinemia II. course and diagnostic and therapeutic problems
Vermeulen, C.; Bouallouche, A.; Brerault, J.L.; Cathelineau, G.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 58(36): 2085-2095
1982
ISSN/ISBN: 0037-1777 PMID: 6294843 Document Number: 192507
Natural growth of prolactinomas unrelated to pregnancy of certain drugs is slow. Mixed adenomas should be systematically looked for since acromegaly or Cushing syndrome may be cured by bromoergocriptine (brc) alone. Management of prolactinomas now rests mainly on bromoergocriptine. Surgery may still be indicated in encapsulated voluminous adenomas, in growing tumors that do not respond to large doses of brc, and in exacerbations during pregnancy which are not rapidly controlled by brc. When hyperprolactinemia does not respond to brc the patient should be investigated for a premenopausal state of a suprasellar lesion.