Diagnostic and therapeutic problems in endangiitis obliterans
Lambrecht, R.; Franke, B.; Heinrich, P.
Zentralblatt für Chirurgie 108(22): 1414-1421
1983
ISSN/ISBN: 0044-409X PMID: 6666417 Document Number: 218033
Out of all patients (n = 313) suffering from peripheral vascular disorders seen at our Department from 1975 to 1981 21 patients had Buerger's disease (Thrombendangitis obliterans). In 4 of them immunological deposits could be traced in the basement membrane of their capillaries. In our opinion nicotine has a stimulating immunological effect on the vessel wall and can be considered as the trigger mechanism for Buerger's disease.