Blood serum somatomedin activity in children with bone tumors

Vasil'eva, I.A.; Ionov, A.A.; Borodina, A.F.

Voprosy Onkologii 28(7): 38-41

1982


ISSN/ISBN: 0507-3758
PMID: 6954761
Document Number: 192399
Blood somatomedin levels were assayed biologically in 10 children with Ewing's sarcoma and osteosarcoma and 11 children with other benign tumors. The patients were of the same age. The basal level of somatomedin in malignant bone sarcoma was similar to that in controls. However, after glucose loading, the patterns of somatomedin level curve in children and adults with normal lipo-carbohydrate metabolism were different. The difference may be due either to the specific features of child's organism or a rise in the level of blood somatomedin inhibitors.

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