Demonstration of the presence of an ultrafiltrable substance in human serum activating somatomedin a
Heulin, M.H.; Artur, M.; Straczek, J.; Malaprade, D.; Pierson, M.; Stoltz, J.F.; Belleville, F.; Paysant, P.; Nabet, P.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 175(3): 364-371
1981
ISSN/ISBN: 0037-9026 PMID: 6456047 Document Number: 171915
Human serum contains an ultrafiltrable factor which stimulates the somatomedin activity measured by 35SO4 incorporation into pelvic cartilage of chick embryo, this ultrafiltrable factor activates native serum somatomedin or partially purified somatomedin. The molecular weight determined by fractionated ultrafiltration or chromatography on Biogel P2 is about 350-500 daltons.