Serum fibronectin and somatomedin-C as nutritional markers in adults receiving total parenteral nutrition
Powers, D.A.; Franse, V.L.; Brown, R.O.; Hinson, A.; Cowan, G.S.
Clinical Pharmacy 7(12): 889-893
1988
ISSN/ISBN: 0278-2677 PMID: 3145166 Document Number: 314474
Serum concentrations of fibronectin and somatomedin-C were estimated in 21 mainly general surgical patients, male or female, before start of total parenteral nutrition by central vein and on days 4, 7, 14 and 21. Other serum indices, including albumin and triglycerides, and nitrogen balance were monitored regularly. Fibronectin was significantly higher throughout treatment than before, whereas somatomedin-C was significantly increased only on day 4. Both substances were poorly correlated with N balance. During week 1 positive balance was attained by 14 patients.