In vitro evaluation of B-lymphocyte function in turkeys infected with hemorrhagic enteritis virus
Nagaraja, K.V.; Emery, D.A.; Patel, B.L.; Pomeroy, B.S.; Newman, J.A.
American Journal of Veterinary Research 43(3): 502-504
1982
ISSN/ISBN: 0002-9645 PMID: 6280530 Document Number: 192312
Studies were conducted on B-lymphocyte function in turkeys infected with hemorrhagic enteritis (HE) virus. Hemolytic plaque-forming technique was used to detect antibody-forming cells in turkeys. The plaque-forming cell responses in HE virus-infected and noninfected controls were compared. Results of this study indicated a decreased capability of HE virus-infected turkeys to produce antibodies to sheep RBC. The greatest inhibition of antibody-forming cell production was seen in the turkeys 19 days after exposure to the virus. However, after this period, the turkeys gradually recovered their immunocompetence to sheep RBC.