Difference in androgen-dependent change of non-histone proteins between dorsolateral and ventral prostates of rats
Matuo, Y.; Nishi, N.; Negi, T.; Wada, F.
Biochemical and Biophysical Research Communications 107(1): 209-216
1982
ISSN/ISBN: 0006-291X PMID: 7126203 Document Number: 192036
A novel species of non-histone protein having a MW of .apprx. 20,000 (20K), abundantly localized in the dorsolateral prostate, was decreased in content by castration and restored by replacement of androgen, in addition to non-histone proteins of MW .gtoreq. 34,000. The content of 20K/DNA was more rapidly decreased by castration, but more slowly restored by replacement of androgen, with the dorsolateral prostate than the ventral prostate. Of other nuclear proteins, non-histone proteins of MW .gtoreq. 90,000 in the dorsolateral prostate were more susceptible to the decrease by castration, while those of all kinds of histones were hardly dependent on the androgen level.