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Comparative study of Salmonella typhimurium strains of various origins in murine models of enteral and intranasal infection

Iakovleva, O.N.; Lycheva, T.A.; Petrovskaia, V.G.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 9: 53-57

1982

ISSN/ISBN: 0372-9311
PMID: 6755986
Document Number: 190882
Antibiotic-resistant S. typhimurium strains of different origin (isolated from patients in cases of hospital infections and enteral toxico-infections, as well as from water), when studied in experimental enteral and intranasal infection of mice showed, in comparison with antibiotic-sensitive strains, less pronounced lethal action and, accordingly, lower capacity for reproduction in the organs of the reticulo-endothelial system of mice. Multiresistant strains isolated from humans in enteral toxico-infections kill orally infected mice more frequently than strains isolated in hospital infections.

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