A new correlation study of HPLC chromatogram with antifungal activity of macrolide polyenes
Swami, M.B.; Nanda, R.K.
Hindustan Antibiotics Bulletin 24(1-2): 1-8
1982
ISSN/ISBN: 0018-1935 PMID: 7107310 Document Number: 189976
A comparison was made between hamycin and aureofungin to show the similarity and differences between the 2 antibiotics based on the retention times of their components using high pressure liquid chromatography. A computer program was developed to predict the potency of each antibiotic from a knowledge of the major polar and non-polar component ratios found from the chromatogram.
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