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Action of thyroid hormones and somatotropin on the free radical, iron-sulfur protein and cytochrome P-450 state in the liver

Martynenko, F.P.; Beregovskaia, N.N.; Polikarpova, N.I.; Iurkovskaia, T.N.

Problemy Endokrinologii 28(3): 69-71

1982

ISSN/ISBN: 0375-9660
PMID: 6285335
Document Number: 189459
The state of free radicals, iron-sulphuric proteins and cytochrome P-450 was determined in hypo- and hyperthyroid rats by means of EPR method. It was shown that EPR signal of cytochrome P-450 was increased in the liver of thyroidectomized rats, characterized by somatotropin deficiency and delayed metabolism. It decreased under the action of exogenous somatotropin both in intact and in thyroidectomized animals. Cytochrome P-450 was lowered in hyperthyroid rats, characterized by intensified oxidative processes without signs of the enhanced hepatic growth. The feedback between the intensified hepatic oxidative processes and the activity of cytochrome P-450-dependent multipurposeful oxidases is suggested.

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Saprin, A.N.; Kalinina, E.V.; Serezhenkov, V.A.; Kotova, I.N.; Solomka, V.S.; Shcherbak, N.P. 2006: Changes in the free-radical state and level of free iron during the formation of drug resistance in tumor cells Biofizika 51(3): 485-490
Lazarev, S.M.; Korableva, N.P. 2006: State of free radical processes, metabolism of nitrogen oxide, iron and cortisol level in autohemotransfusion and transfusion of the donor blood Vestnik Khirurgii Imeni I. I. Grekova 165(5): 72-75
Panin, L.E.; Kuz'menko, D.I. 1991: Features of oxidation of reserve lipids in liver mitochondria during starvation: the role of non-heme iron and free radical fatty acid oxidation Voprosy Meditsinskoi Khimii 37(3): 5-9
Abdullina, L.R.; Safuanova, G.Sh.; Nikulicheva, V.I.; Kamilov, F.Kh.; Ianturina, N.Kh. 2007: Time course of changes in clinical and hematological parameters, iron metabolism, and free radical lipid oxidation in patients with iron-deficiency anemia during multimodality treatment Klinicheskaia Laboratornaia Diagnostika 2007(8): 41-43
Chirangini, P.; Sharma, G.J.; Sinha, S.K. 2004: Sulfur free radical reactivity with curcumin as reference for evaluating antioxidant properties of medicinal zingiberales Journal of Environmental Pathology Toxicology and Oncology: Official Organ of the International Society for Environmental Toxicology and Cancer 23(3): 227-236
Galante, Y.M.; Hatefi, Y. 1978: Resolution of complex i and isolation of NADH dehydrogenase and an iron--sulfur protein Methods in Enzymology 53: 15-21
Voloshchuk, O.N.; Kopylchuk, G.P. 2015: Peculiarities of the Structural-Functional State of the Cytochrome Part of Liver Mitochondrial Respiratory Chain under Conditions of Acetaminophen-induced Hepatitis against the Background of Alimentary Deprivation of Protein Biofizika 60(3): 519-524
Schneider, D.; Jaschkowitz, K.; Seidler, A.; Rögner, M. 2000: Overexpression and reconstitution of a Rieske iron-sulfur protein from the cyanobacterium Synechocystis PCC 6803 Indian Journal of Biochemistry and Biophysics 37(6): 441-446
Harrelson, W.G.; Mason, R.P. 1982: Microsomal reduction of gentian violet. Evidence for cytochrome P-450-catalyzed free radical formation Molecular Pharmacology 22(2): 239-242
Borek, A.; Ekiert, R.; Osyczka, A. 2016: Molecular effects of mitochondrial mutations in cytochrome b of complex IIi and their impact on the levels of free radical production Postepy Biochemii 62(2): 162-172
Mihara, H. 2011: Discovery and molecular function analysis of sulfur- and selenium-eliminating enzymes crucial for biosynthesis of iron-sulfur clusters and selenoproteins Seikagaku. Journal of Japanese Biochemical Society 83(11): 1003-1015
Graziano, J.H. 1976: Potential usefulness of free radical scavengers in iron overload Birth Defects Original Article Series 12(8): 135-143
Ghinea, E.; Dumitriu, L.; Stefanovici, G.; Pop, A.; Damian, A.; Handoca, A.; Stanciu, R. 1988: Protein content and thyroid hormone release in vitro by differentiated thyroid cancer cells in the presence of estradiol, dehydroepiandrosterone, polypeptidic hormones and pesticides Endocrinologie 26(3): 165-171
Stamatiadis, A.P.; Zombolas, B.T.; Tsitsiridis, M.E.; Kyriakos, G.M.; Manouras, A.J.; Apostolidis, N.S. 1990: Changes in free thyroid hormones after epidural anesthesia Minerva Chirurgica 45(23-24): 1467-1468
Gibson, K.; Harris, P. 1974: The effects of a number of hormones on myocardial cell free protein biosynthesising systems and on the uptake of 14C-phenylalanine into protein in the perfused heart system Research Communications in Chemical Pathology and Pharmacology 8(2): 313-318
Takahashi, Y.; Goldschmidt-Clermont, M.; Soen, S.Y.; Franzén, L.G.; Rochaix, J.D. 1991: Directed chloroplast transformation in Chlamydomonas reinhardtii: insertional inactivation of the psaC gene encoding the iron sulfur protein destabilizes photosystem I EMBO Journal 10(8): 2033-2040
Pangjit, K.; Tantiphaipunwong, P.; Sajjapong, W.; Srichairatanakool, S. 2014: Iron-chelating, free radical scavenging and anti-proliferative activities of Azadirachta indica Journal of the Medical Association of Thailand 97(Suppl 4): S36-S43
Obraztsov, V.V.; Glushchenko, N.N.; Orlov, S.N.; Danilov, V.S. 1975: Free radical oxidation of biological membrane lipids. IV. iron salts in peroxidation catalysis of linoleic acid Biofizika 20(1): 93-97
Saatov, T.S.; Burkhanov, S.A.; Usmanova, G.U. 1984: Changes in the ganglioside composition of various rat organs under the action of thyroid hormones Biokhimiia 49(8): 1291-1294
Ruuge, E.K.; Kerimov, T.M.; Panemanglor, A.V. 1976: Effect of lyophilization on the free-radical state of animal cells Biofizika 21(1): 124-128