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Antitumor activity of total saponins from Dolichos falcatus Klein

Huang, H.P.; Cheng, C.F.; Lin, W.Q.; Yang, G.X.; Song, J.Y.; Ren, G.Y.

Zhongguo Yao Li Xue Bao 3(4): 286-288

1982

ISSN/ISBN: 0253-9756
PMID: 6219550
Document Number: 186312
The total saponins, isolated from the root of Dolichos falcatus Klein, administered i.p. to mice showed a marked antitumor activity on sarcoma 37 but no effects on sarcoma 180, cervical carcinoma U14, Ehrlich ascites carcinoma and Ehrlich solid carcinoma. The saponins caused a direct lethal cytotoxicity on S37 in vitro, but had no effect on the phagocytic index of peritoneal phagocytes in the mice.

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