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Antitumor effects of total alkaloids isolated from Solanum nigrum in vitro and in vivo

Li, J.; Li, Q-Wang.; Gao, D-Wei.; Han, Z-Sheng.; Li, K.

Die Pharmazie 63(7): 534-538

2008

ISSN/ISBN: 0031-7144
PMID: 18717490
Document Number: 627501
This study demonstrated that the total alkaloids isolated from the traditional Chinese medicinal herb Solarium nigrum Linne (SNL-A) inhibited the growth of human cervical cancer HeLa cells in culture medium with much lower toxicity to human normal lymphocytes. By means of HE staining and TUNEL assay, our results further revealed that SNL-A induced cell death by apoptosis.

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