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Characteristics of the causative agent and of the immunological status of the body in experimental dormant staphylococcal infection

Shilov, A.B.; Romanov, V.A.; Malafeeva, E.V.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 74-77

1982

ISSN/ISBN: 0372-9311
PMID: 7080764
Document Number: 184978
Pathogenic staphylococci were found to persist in the focus of dormant infection in guinea pigs till day 100 of the experiment without changing their biological properties and sensitivity to antibiotics. The latent period of dormant staphylococcal infection was characterized by the increasing titers of antibodies to staphylococcal autostrains, by the positive results of the intradermal allergic test and the macrophage migration inhibition test with hemolytic staphylococcal allergen, as well as by the suppression of serum lysozyme activity. No changes in the content of complement and the total bactericidal activity of blood serum were detected.

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