Effect of sub-pressor doses of dopamine on renin secretion in the anesthetized dog
Posadas, C.; Boyer, J.L.; Guzmán, J.; Figueroa, J.; Millán, A.; Sánchez, G.; Serrano, P.A.
Archivos del Instituto de Cardiologia de Mexico 51(1): 13-19
1981
ISSN/ISBN: 0020-3785 PMID: 7011235 Document Number: 182589
The effects of dopamine, its precursor L-dopa, and the dopaminergic agonist bromocriptine (BEC), on plasma renin activity (PRA), in pentobarbital anesthetized male dogs were investigated. Infusion of dopamine at a dose which did not change blood pressure (4 ug/kg per min) had no effect on the secretion of renin, nor did it produce modifications in the PRA response to furosemide (10 mg i.v.). L-dopa, in single dose of 500 mg (p.o formed in peripheral tissues from administered L-dopa.