Improvement of bleeding time, platelet aggregation and platelet count during CAPD treatment
Arends, J.P.; Krediet, R.T.; Boeschoten, E.W.; van der Lelie, J.; Veenhof, C.H.; von dem Borne, A.E.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association 18: 280-285
1981
ISSN/ISBN: 0071-2736 PMID: 7329972 Document Number: 180243
Mean bleeding time in 11 uraemic patients improved from 11.2 (range 3.5--20) before the 5.8 (range 2.5--20) minutes during CAPD treatment (p less than 0.025). Bleeding time became normal in six out of seven patients with a prolonged bleeding time prior to CAPD. There was a concomitant improvement in platelet aggregation. Mean platelet count rose from 195 (range 117--414) to 311 (148--522) x 10(9)/L (p less than 0.01). A significant correlation was found between the change in bleeding time and in platelet aggregation induced by ristocetin, but not between the change in bleeding time and the platelet count. Our results suggest that CAPD treatment improves the uraemic bleeding tendency, even in patients on previous haemodialysis treatment.