The effect of neostigmine and atropine on gastro-oesophageal reflux
Pflücke, V.F.; Anders, O.; Schreiber, H.
Deutsche Zeitschrift für Verdauungs- und Stoffwechselkrankheiten 41(6): 270-275
1981
ISSN/ISBN: 0012-1053 PMID: 7341219 Document Number: 180182
During 6 hours continuous pH-measurements were undertaken to study the effect of neostigmine (0,5 mg s.c.) and atropine (0,5 mg s.c.) on gastro-oesophageal reflex after a standardised meal (n=18). Mean total reflux duration, single reflux duration and mean reflux frequency were not effected by neostigmine. Mean total reflux duration and mean reflux frequency were not effected by neostigmine. Mean total reflux duration and mean reflux frequency were reduced by atropine during the first hour p.i. (a less than 0,01).