Specific I125-insulin binding in the plasma membrane of adipose tissue cells in pheochromocytoma
Bezdrobnyĭ, I.V.; Evdokimova, N.I.; Efimov, A.S.; Komissarenko, I.V.; Demchenko, N.P.
Problemy Endokrinologii 27(5): 38-42
1981
ISSN/ISBN: 0375-9660 PMID: 7027250 Document Number: 180173
Specific 125I-insulin binding with the fat cellular plasma membranes was studied in 7 patients with pheochromocytoma. It was shown that the concentration of insulin receptors in plasma membranes and their affinity to insulin decreased and the negative cooperative interaction between receptors rose in patients with pheochromocytoma comparatively to normal subjects.
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