Mitotic regimen of different histological variants of lymphosarcoma
Kazantseva, I.A.; Probatova, N.A.
Arkhiv Patologii 43(10): 11-18
1981
ISSN/ISBN: 0004-1955 PMID: 7032476 Document Number: 177809
Mitotic regimen of lymphosarcoma (75 observations), angiofollicular hyperplasia (5) and reactive hyperplasia of lymph nodes of the follicular type (34 observations--a group for comparison) was studied. The mitotic regimen values of non-Hodgkin's malignant lymphomas were found to vary in accordance with the morphological variant of the tumor. A higher mitotic activity in combination with high frequency and diversity of forms of mitosis pathology was typical of lymphoblast and immunoblast lymphosarcomas only. Prolymphocytic lymphosarcomas showed a relatively low mitotic activity. Lymphosarcoma with nodular growth showed a considerable decrease in mitotic activity as compared with nodular reactive hyperplasia. The emergence of multipolar mitoses is a reliable diagnostic sign of nodular lymphosarcoma.