A clinicopathologic study of endometrial carcinoma with special reference to new histological variants
Sato, Y.; Ozaki, M.; Ueda, G.; Tanizawa, O.
Nihon Sanka Fujinka Gakkai Zasshi 37(6): 1015-1019
1985
ISSN/ISBN: 0300-9165 PMID: 2991395 Document Number: 245651
The clinical and pathological features of 229 patients with endometrical carcinoma were analyzed with special reference to new histological variants. Histologically, 187 endometrial carcinomas were endometrioid form of adenocarcinoma, 10 mucinous carcinoma, 8 papillary serous carcinoma, 5 clear cell carcinoma, 1 secretory carcinoma, and 18 adenocarcinoma with squamous differentiation. Of these, papillary serous carcinoma was found to be a highly malignant form of endometrial carcinoma. Clear cell carcinoma was also associated with a poor prognosis. No fatal cases were observed in patients with mucinous carcinoma, secretory carcinoma, and adenocarcinoma with squamous differentiation. Patients with endometrioid form of adenocarcinoma were prognostically in between. Analysis of the patients with poor prognosis revealed that the length of time between onset of symptoms and surgery was not related to surviving periods and other prognostic factors such as clinical stage, histological grade, and myometrial invasion.