Diabetes mellitus is a multivariate independent prognostic factor in endometrial carcinoma: a clinicopathologic study on 313 patients
Steiner, E.; Plata, K.; Interthal, C.; Schmidt, M.; Faldum, A.; Hengstler, J.G.; Sakuragi, N.; Watari, H.; Yamamoto, R.; Kölbl, H.
European Journal of Gynaecological Oncology 28(2): 95-97
2007
ISSN/ISBN: 0392-2936 PMID: 17479668 Document Number: 613900
Objective: The aim of this study was to analyse the influence of diabetes mellitus as a prognostic factor for overall survival in endometrial cancer. Materials and Methods: Charts were reviewed from patients with endometrial carcinoma from 1985 to 2003. Data on clinicopathologic variables, adjuvant treatment, site of recurrence and Survival were collected. The chi-square test was used to examine associations between variables. The Kaplan-Meier method was used for survival analysis and Cox's proportional hazards model for multiple regression analysis. Results: Multivariate analysis revealed that diabetes mellitus, FIGO stage and depth of myometrial invasion were significantly associated with overall survival.