Effect of some stressors on the mitotic regimen of the corneal epithelium and on the level of aneuploid bone marrow cells of adrenalectomized albino rats
Timoshin, S.S.; Simon, N.B.; Baranov, A.P.
Biulleten' Eksperimental'noi Biologii i Meditsiny 88(9): 338-341
1979
ISSN/ISBN: 0365-9615 PMID: 519027 Document Number: 150925
It has been shown that pyrogenal administration or one-hour hyporthermia at 28--30 degrees C did not induce development of reactive inhibition in adrenalectomized rats but produced a significant increase in the level of pathological mitoses in the cornea of intact (from 4.3% to 6.3%) and adrenalectomized (from 10.6% to 12.5%) rats subjected to stress. The karyotypic analysis of the bone marrow cells under such conditions showed a significant rise in the number of aneuploid (hupo- and hyperdiploid) cells.