Evaluation of the bactericidal activity of chiral alkylammonium salts derived from N-benzoyl-amino acids with Escherichia coli and Bacillus cereus. II. -- Adsorption mechanism and interpretation

Massé, J.; Thévenard, B.

Pathologie-Biologie 29(8): 473-480

1981


ISSN/ISBN: 0369-8114
PMID: 6795577
Document Number: 177152
By testing the antibacterial activity of new long-chained alkylammonium salts with organic asymmetric anions (N-benzoyl-amino-acids) we have been able to precise the kind of interaction that would take place between the microorganisms and the two groups of the surfactant molecule. Evidence for anion participation to the bactericidal activity appeared through kind and configuration of the amino acid. A mechanism is proposed, that takes into account, hydrophobic and ionic interactions with cation and anion participation.

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