Formation of foci of myeloid cells on colonies of thymus and bone marrow fibroblasts in monolayer cultures
Kuznetsov, S.A.; Luriia, E.A.; Genkina, E.N.
Biulleten' Eksperimental'noi Biologii i Meditsiny 91(5): 610-613
1981
ISSN/ISBN: 0365-9615 PMID: 7260394 Document Number: 176583
A culture system favouring myeloid cell formation directly on the surface of mouse stromal fibroblast colonies has been developed. It has been shown that the plaques formed are both much more numerous and essentially larger on stromal fibroblast colonies of thymus than of bone marrow origin. Consequently, hemopoietic precursor cells that form the myeloid plaques in the monolayer cultures interact dissimilarly with stromal mechanocytes of different origin.