Intralesional 5-Fluorouracil in the Treatment of Lower Leg Squamous Cell Carcinoma
Mackey, M.; Shahsavari, A.; Mackey, V.. T.
Journal of Drugs in Dermatology Jdd 17(11): 1241-1243
2018
ISSN/ISBN: 1545-9616 PMID: 30500149 Document Number: 17637
Non-melanoma skin cancer (NMSC) is the most commonly diagnosed cancer in the United States.1,2 There are different treatment modalities for non-melanoma skin cancer, that include surgical excision, radiation therapy, cryotherapy, electrodessication and curettage, photodynamic therapy, and topical chemotherapy. Intralesional injection with 5-fluorouracil is a treatment modality that is not used often, perhaps due to not much research available to its effectiveness or established treatment recommendations. We report a case of a patient with multiple lesions of cutaneous squamous cell carcinoma on the lower extremities treated successfully with intralesional 5- fluorouracil.
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