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Experimental basis for associated subcutaneous jet injection immunization against plague and smallpox

Gapochko, K.G.; Gamleshko, K.P.; Gerasiuk, L.G.; Emel'ianova, O.V.; Litvinova, A.P.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1: 65-69

1981

ISSN/ISBN: 0372-9311
PMID: 7234244
Document Number: 175896
Experiments in guinea-pigs have indicated that combined immunization with the mixture of live plague and smallpox vaccines introduced subcutaneously by means of a jet injector are safe and faintly reactogenic. Highly intense immunity, as revealed by serological shifts and by the degree of protection of the vaccinated animals challenge with the virulent cultures of the corresponding infective agents, allows the recommendation that combined subcutaneous immunization against plague and smallpox by means of a jet injector be further studied on humans.

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