Prevalence of Chronic Hepatitis B Infection in Patients with Systemic Lupus Erythematosus: Viral Reactivation and Impact on Disease Activity
Sumethkul, K.; Srivitidkul, S.
Journal of the Medical Association of Thailand 100(Suppl 1): S124-S130
2017
ISSN/ISBN: 0125-2208 PMID: 29927230 Document Number: 17478
Hepatitis B virus (HBV) infection is prevalent in many parts of the world, especially in South East Asia, and A cross-sectional study was conducted between November 2013 and February 2014 to determine the One hundred and thirty-four Thai SLE patients were included in the study, and the prevalence of HBV infection in these patients was 1.5% (2/134), which is lower than in the Thai general population. No differences were found between clinical manifestations of SLE, abnormal laboratory investigations, and treatments of patients with HBsAg positive SLE patients and those of HBsAg-negative patients. Neither HBsAg-positive SLE patients nor those who were HBsAg negative had cirrhosis or hepatocellular carcinoma. Neither group had evidence of acute transaminitis during their disease course, even though one patient had high HBV viremia and had not received any antiviral prophylaxis. The results showed that the prevalence of chronic HBV infection in SLE patients was lower than in the general