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Plasma protein concentration and recovery from anaesthesia in man

Torri, G.; Stella, L.; Pradella, G.; Maestrone, E.; Martani, C.

British Journal of Anaesthesia 53(12): 1281-1284

1981

ISSN/ISBN: 0007-0912
PMID: 7317247
Document Number: 174585
The effect of plasma protein concentration on the recovery from anesthesia induced by equipotent doses (UD95) of thiopentone and Althesin was studied in 48 patients. The recovery time (RT) was plotted against the concentrations of total plasma proteins (TPP) and albumin (Al). A small decrease in TPP concentration from normal range affected the recovery time minimally; a small decrease in TPP concentration from a low basal value markedly increased the recovery time with both agents. A large decrease in TPP concentration markedly increased the recovery time from thiopentone and Althesin.

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