High performance liquid chromatographic analysis of hydrocortisone acetate ointments: interlaboratory study
Hailey, D.M.; Lea, A.R.
Journal - Association of Official Analytical Chemists 64(4): 870-874
1981
ISSN/ISBN: 0004-5756 PMID: 7275903 Document Number: 172381
An interlaboratory study was carried out on a high performance liquid chromatographic method for determining hydrocortisone acetate in ointments. The method represents an alternative to the colorimetric procedure of the British Pharmacopoeia. Two samples of a commercially available hydrocortisone acetate ointment were analyzed by 14 laboratories. Column performance and precision of the assay were satisfactory. The total error standard deviation for the method was 3.69%.