High performance liquid chromatographic analysis of hydrocortisone acetate ointments: interlaboratory study

Hailey, D.M.; Lea, A.R.

Journal - Association of Official Analytical Chemists 64(4): 870-874

1981


ISSN/ISBN: 0004-5756
PMID: 7275903
Document Number: 172381
An interlaboratory study was carried out on a high performance liquid chromatographic method for determining hydrocortisone acetate in ointments. The method represents an alternative to the colorimetric procedure of the British Pharmacopoeia. Two samples of a commercially available hydrocortisone acetate ointment were analyzed by 14 laboratories. Column performance and precision of the assay were satisfactory. The total error standard deviation for the method was 3.69%.

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