Evaluation of the activity on the mouse CNS of several plant extracts and a combination of them
Della Loggia, R.; Tubaro, A.; Redaelli, C.
Rivista di Neurologia 51(5): 297-310
1981
ISSN/ISBN: 0035-6344 PMID: 6118937 Document Number: 169222
Some activities of seven vegetable extracts and an association of them given by oral route were tested on the C.N.S. of the mouse. Among these, Crataegus oxyacantha and, less clearly, Valeriana officinalis show some sedative activity, whereas the extract from Passiflora incarnata gives some anxiolytic effect. Matricaria chamomilla and Piscidia erythrina stand in an intermediate position between the previous ones. Hyoscyamus niger proved to be active in only one of the tests performed, whereas Atropa belladonna did not show any activity on the C.N.S. The association of the seven extracts seemed to act in a synergetic way, the resulting activity being sedative at high dosage and anxiolytic at low dosage.