In vitro effect of isoprinosine on rabies virus
Hernández-Jáuregui, P.; González-Vega, D.; Cruz-Lavín, E.; Hernández-Baumgarten, E.
American Journal of Veterinary Research 41(9): 1475-1478
1980
ISSN/ISBN: 0002-9645 PMID: 6160794 Document Number: 167962
The in vitro effect of isoprinosine, an antiviral compound, was evaluated on ERA and V319 rabies viral strains. Isoprinosine diminished the number of immunofluorescent cells, viral titers and structures involved in rabies virus replication. Mechanism of antiviral action was probably mediated by modification of the polyribosome conformation and function. [Hamster kidney cells were used.].
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