Cytoskeletal control of concanavalin A receptor mobility in isolated rat hepatocytes
Devirgiliis, L.C.; Dini, L.; Stefanini, S.; Autuori, F.
Cellular and Molecular Biology Including Cyto-Enzymology 26(5): 533-540
1980
ISSN/ISBN: 0145-5680 PMID: 7000354 Document Number: 164165
The effect of colchicine on the mobility of Concanavalin A (Con A) receptors in the membrane of isolated rat hepatocytes was studied. The drug was injected in vivo or alternatively isolated hepatocytes were treated in vitro. Receptor mobility was assessed by estimating the percentage of cells exhibiting cap formation following incubation with fluorescein-labeled Con A (Con A-FITC). The Con A receptor distribution was also examined at the ultrastructural level by Con A peroxidase technique.